Environmental Impact of Moxidectin

We’d like to draw your attention to the following update to the SPCs (Summary of Product Characteristics) for moxidectin products (specifically the ‘Cydectin’ and ‘Zermex’ ranges): ‘Moxidectin fulfils the criteria for a (very) persistent, bioaccumulative and toxic (PBT) substance; therefore, exposure of the environment to moxidectin must be limited… Treatments should be administered only when […]

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We’d like to draw your attention to the following update to the SPCs (Summary of Product Characteristics) for moxidectin products (specifically the ‘Cydectin’ and ‘Zermex’ ranges):

‘Moxidectin fulfils the criteria for a (very) persistent, bioaccumulative and toxic (PBT) substance; therefore, exposure of the environment to moxidectin must be limited… Treatments should be administered only when necessary and should be based on faecal egg counts or evaluation of the risk of infestation at the animal and/or herd level.

Like other macrocyclic lactones, moxidectin has the potential to adversely affect non-target organisms…’

Treated animals may excrete moxidectin-containing faeces onto pasture, temporarily reducing the abundance of dung feeding organisms such as dung flies and dung beetles. If you need to administer repeated treatments of moxidectin (or other products in the same anthelmintic class) it is advisable not to treat animals every time on the same pasture, to allow dung fauna populations to recover.

Moxidectin is also toxic to aquatic organisms including fish. Only use the product according to the label instructions, and do not allow treated animals to have access to watercourses during the first 10-11 days after treatment.

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